Welcome to MeDBA
MeDBA aims to provide an integrated, distinctive, practicable, user-friendly platform for metalloenzyme-focused data bank and analysis. It integrates information regarding metalloenzymes, ligands, metalloenzyme-ligand associations with metalloenzyme-specific analysis tools, which will help understand and investigate metalloenzyme-involved contents, and will promote and bridge metalloenzyme-related areas (e.g., biological chemistry, structural and chemical biology, synthetic biology, bioinorganic chemistry, medicinal chemistry, computational chemistry and drug discovery). MeDBA is developed and maintained by Prof. Guo-Bo Li's group.
Latest release
July 15, 2022
- Updated help materials
- Updated visit statistics
- Minor bug and performance fixes
MeDBA Statistics
No. of metalloenzymes | 82540 |
No. of human metalloenzymes | 1634 |
No. of metalloenzyme families (InterPro) | 6837 |
No. of metalloenzyme-related diseases (ICD-11) | 826 |
No. of metalloenzyme-related diseases (MeSH) | 923 |
No. of metalloenzyme structures | 50892 |
No. of metalloenzyme structure models | 21616 |
No. of metal site classes | 1738 |
No. of metalloenzyme-ligand complexes | 10613 |
No. of metalloenzyme-protein complexes | 5821 |
No. of metalloenzyme-DNA/RNA complexes | 3922 |
No. of metal binding pharmacophores | 844 |
No. of bioactive ligands | 431014 |
No. of metalloenzyme substrates/products | 2243 |
No. of PROTACs targeting metalloenzymes | 1415 |
No. of drugs targeting metalloenzymes | 566 |
No. of drug candidates targeting metalloenzymes | 6942 |